Verfügbarkeit: Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.

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Titel:	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.
Von:	vorgelegt von Josef Maximilian Herrmann
Person:	Herrmann, Josef Maximilian 1983- Verfasser aut
Hauptverfasser:	Herrmann, Josef Maximilian 1983- (VerfasserIn)
Format:	Hochschulschrift/Dissertation Buch
Sprache:	Englisch
Veröffentlicht:	2013
Notation:	VK 5075
Schlagwörter:	Naturstoff Mäusedorn Chemische Synthese Alkohole Desoxygenierung Hochschulschrift
Medienzugang:	http://epub.uni-regensburg.de/28806/ https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-288069 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027485022&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
Umfang:	145 S. Ill., graph. Darst.

Internformat

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Datensatz im Suchindex

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adam_text	TABLE OF CONTENTS 1 REDUCTIVE DEOXYGENATION OF ALCOHOLS - CATALYTIC METHODS BEYOND BARTON MCCOMBIE DEOXYGENATION 3 1.1 INTRODUCTION 3 1.2 DEOXYGENATIONS EMPLOYING A TWO-STEP PROCEDURE 5 1.2.1 DEOXYGENATION OF ALCOHOL DERIVATIVES (ETHERS, ESTERS) 5 1.2.2 DEOXYGENATION OF ALCOHOLS VIA ELIMINATION-HYDROGENATION SEQUENCE 1S 1.3 DIRECT REDUCTIVE DEOXYGENATION OF ALCOHOLS 18 1.3.1 DIRECT DEOXYGENATION WITH HYDROGENATION CATALYSTS 18 1.3.2 (LEWIS) ACID CATALYZED DIRECT DEOXYGENATIONS 21 1.4 CONCLUSION 26 1.5 REFERENCES 27 2 REDUCTION OF BENZYLIC ALCOHOLS AND A-HYDROXYCARBONYL COMPOUNDS BY HYDRIODIC ACID IN A BIPHASIC REACTION MEDIUM 33 2.1 INTRODUCTION 33 2.2 RESULTS AND DISCUSSION 34 2.2.1 DEOXYGENATION OF BENZYLIC ALCOHOLS 34 2.2.2 DEOXYGENATION OF ALLYLIC AND PROPARGYLIC ALCOHOLS 36 2.2.3 CONVERSION OF ALIPHATIC ALCOHOLS WITHOUT JI-SYSTEM IN A-POSITION 37 2.2.4 MECHANISM OF THE DEOXYGENATION WITH HYDRIODIC ACID 38 2.2.5 DEOXYGENATION WITH CATALYTIC AMOUNTS OF HYDRIODIC ACID 39 2.3 CONCLUSIONS 41 2.4 EXPERIMENTAL 42 2.5 REFERENCES 46 HTTP://D-NB.INFO/1058713574 3 SYNTHESIS OF NOVEL NATURAL PRODUCTS ISOLATED FROM BUTCHERS BROOM 51 3.1 BENZOXEPINES ISOLATED FROM BUTCHERS BROOM 51 3.2 SYNTHESIS OF THE RUSCOZEPINES AND ANALOGOUS BENZOXEPINES 53 3.2.1 RUSCOZEPINE A, B AND ANALOGOUS BENZOXEPINES 55 3.2.2 SYNTHESIS OF 8-METHOXY-2,3-DIHYDROBENZO[B]OXEPIN-7-OL 65 3.2.3 NITROGEN ANALOG OF RUSCOZEPINES - BENZAZEPINE 66 3.3 PHARMACOLOGY 67 3.3.1 RHIZOMA EXTRACT OF RUSCUS ACULEATUS L 67 3.3.2 MTT VIABILITY ASSAY - CYTOTOXICITY 67 3.3.3 ICAM-1 EXPRESSION INHIBITION ASSAY - ANTI-INFLAMMATORY ACTIVITY 68 3.3.4 ORAC-FLUORESCEIN ASSAY - ANTIOXIDANT ACTIVITY 70 3.4 CONCLUSION 72 3.5 EXPERIMENTAL 73 3.5.1 PREPARATION OF COMPOUNDS 73 3.5.2 PHARMACOLOGICAL TESTING 107 3.6 REFERENCES 109 4 SUMMARY ILL 5 ZUSAMMENFASSUNG 112 6 APPENDIX 115 6.1 ABBREVIATIONS 115 6.2 COPIES OF SELECTED NMR - SPECTRA 118 6.3 LIST OF PRESENTATIONS AND PUBLICATIONS 141 6.4 CURRICULUM VITAE 142 6.5 DANKSAGUNGEN 144
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author	Herrmann, Josef Maximilian 1983-
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dewey-tens	540 - Chemistry and allied sciences
discipline	Chemie / Pharmazie
format	Thesis Book
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spellingShingle	Herrmann, Josef Maximilian 1983- Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L. Naturstoff (DE-588)4041418-8 gnd Mäusedorn (DE-588)7518729-2 gnd Chemische Synthese (DE-588)4133806-6 gnd Alkohole (DE-588)4141899-2 gnd Desoxygenierung (DE-588)4149192-0 gnd
subject_GND	(DE-588)4041418-8 (DE-588)7518729-2 (DE-588)4133806-6 (DE-588)4141899-2 (DE-588)4149192-0 (DE-588)4113937-9
title	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.
title_auth	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.
title_exact_search	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.
title_full	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L. vorgelegt von Josef Maximilian Herrmann
title_fullStr	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L. vorgelegt von Josef Maximilian Herrmann
title_full_unstemmed	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L. vorgelegt von Josef Maximilian Herrmann
title_short	Reductive deoxygenation of alcohols & Synthesis of novel natural products isolated from Ruscus aculeatus L.
title_sort	reductive deoxygenation of alcohols synthesis of novel natural products isolated from ruscus aculeatus l
topic	Naturstoff (DE-588)4041418-8 gnd Mäusedorn (DE-588)7518729-2 gnd Chemische Synthese (DE-588)4133806-6 gnd Alkohole (DE-588)4141899-2 gnd Desoxygenierung (DE-588)4149192-0 gnd
topic_facet	Naturstoff Mäusedorn Chemische Synthese Alkohole Desoxygenierung Hochschulschrift
url	http://epub.uni-regensburg.de/28806/ https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-288069 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027485022&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT herrmannjosefmaximilian reductivedeoxygenationofalcoholssynthesisofnovelnaturalproductsisolatedfromruscusaculeatusl

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