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| Title: | Drug Target Selection and Validation |
|---|---|
| From: |
edited by Marcus T. Scotti, Carolina L. Bellera.
|
| Person: |
Scotti, Marcus T.
Bellera, Carolina L. editor. |
| Corporate Author: | |
| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Cham :
Springer International Publishing : Imprint: Springer,
2022.
|
| Edition: | 1st ed. 2022. |
| Series: | Computer-Aided Drug Discovery and Design,
1 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-3-030-95895-4 |
| Summary: | The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases. |
| Physical Description: | 1 Online-Ressource (XV, 257 p. 37 illus., 33 illus. in color.) |
| ISBN: | 9783030958954 |
| ISSN: | 2730-5465 ; |
Staff View
MARC
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| 505 | 0 | |a Drug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies - Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery. | |
| 520 | |a The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases. | ||
| 650 | 0 | |a Pharmacology. | |
| 650 | 0 | |a Pharmaceutical chemistry. | |
| 650 | 0 | |a Drugs |x Design. | |
| 650 | 0 | |a Medicinal chemistry. | |
| 650 | 0 | |a Molecular biology. | |
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| 650 | 2 | 4 | |a Pharmaceutics. |
| 650 | 2 | 4 | |a Structure-Based Drug Design. |
| 650 | 2 | 4 | |a Medicinal Chemistry. |
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| contents | Drug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies - Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery. |
| dewey-full | 615 |
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| edition | 1st ed. 2022. |
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| id | ZDB-2-SBL-978-3-030-95895-4 |
| illustrated | Not Illustrated |
| indexdate | 2025-06-23T13:27:55Z |
| institution | BVB |
| isbn | 9783030958954 |
| issn | 2730-5465 ; |
| language | English |
| open_access_boolean | |
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| physical | 1 Online-Ressource (XV, 257 p. 37 illus., 33 illus. in color.) |
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| publishDate | 2022 |
| publishDateSearch | 2022 |
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| publisher | Springer International Publishing : Imprint: Springer, |
| record_format | marc |
| series | Computer-Aided Drug Discovery and Design, |
| series2 | Computer-Aided Drug Discovery and Design, |
| spelling | Drug Target Selection and Validation [electronic resource] / edited by Marcus T. Scotti, Carolina L. Bellera. 1st ed. 2022. Cham : Springer International Publishing : Imprint: Springer, 2022. 1 Online-Ressource (XV, 257 p. 37 illus., 33 illus. in color.) text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Computer-Aided Drug Discovery and Design, 2730-5465 ; 1 Drug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies - Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery. The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases. Pharmacology. Pharmaceutical chemistry. Drugs Design. Medicinal chemistry. Molecular biology. Pharmaceutics. Structure-Based Drug Design. Medicinal Chemistry. Molecular Biology. Scotti, Marcus T. editor. edt http://id.loc.gov/vocabulary/relators/edt Bellera, Carolina L. editor. edt http://id.loc.gov/vocabulary/relators/edt SpringerLink (Online service) Springer Nature eBook Printed edition: 9783030958947 Printed edition: 9783030958961 Printed edition: 9783030958978 |
| spellingShingle | Drug Target Selection and Validation Computer-Aided Drug Discovery and Design, Drug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies - Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery. Pharmacology. Pharmaceutical chemistry. Drugs Design. Medicinal chemistry. Molecular biology. Pharmaceutics. Structure-Based Drug Design. Medicinal Chemistry. Molecular Biology. |
| title | Drug Target Selection and Validation |
| title_auth | Drug Target Selection and Validation |
| title_exact_search | Drug Target Selection and Validation |
| title_full | Drug Target Selection and Validation [electronic resource] / edited by Marcus T. Scotti, Carolina L. Bellera. |
| title_fullStr | Drug Target Selection and Validation [electronic resource] / edited by Marcus T. Scotti, Carolina L. Bellera. |
| title_full_unstemmed | Drug Target Selection and Validation [electronic resource] / edited by Marcus T. Scotti, Carolina L. Bellera. |
| title_short | Drug Target Selection and Validation |
| title_sort | drug target selection and validation |
| topic | Pharmacology. Pharmaceutical chemistry. Drugs Design. Medicinal chemistry. Molecular biology. Pharmaceutics. Structure-Based Drug Design. Medicinal Chemistry. Molecular Biology. |
| topic_facet | Pharmacology. Pharmaceutical chemistry. Drugs Design. Medicinal chemistry. Molecular biology. Pharmaceutics. Structure-Based Drug Design. Medicinal Chemistry. Molecular Biology. |
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