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Bibliographic Details
Title:Neurophysiologic Biomarkers in Neuropsychiatric Disorders
Etiologic and Treatment Considerations /
From: edited by Daniel C. Javitt, James C. McPartland.
Person: Javitt, Daniel C.
McPartland, James C.
editor.
Corporate Author: SpringerLink (Online service)
Other Authors: Javitt, Daniel C. (Editor), McPartland, James C. (Editor)
Format: Electronic eBook
Language:English
Published: Cham : Springer Nature Switzerland : Imprint: Springer, 2024.
Edition:1st ed. 2024.
Series:Advances in Neurobiology, 40
Subjects:
Online Access:https://doi.org/10.1007/978-3-031-69491-2
Summary:This book reviews neurophysiological biomarkers in neuropsychiatric disorders from the viewpoint of the 21st Century Cures Act, which encourages the use of biomarkers for a variety of purposes during drug development. It covers both traditional etiologic uses of biomarkers and the more recent Biomarkers, EndpointS, and other Tools (BEST) classification scheme used by the FDA, which permits biomarkers for purposes of susceptibility, diagnosis, monitoring, prognosis, pharmacodynamics/response, and safety. The first section of the book describes potential uses of neurophysiologic biomarkers. Subsequent sections focus on a wide range of conditions, including schizophrenia, autism spectrum disorder, Parkinson's disease, and depression, as well as cross-diagnostic and translational uses, including monkey and rodent analogs. The purpose of the book is to help clinicians understand how neurophysiological biomarkers may be used to understand and manage clinical conditions; to help researchers to understand how biomarkers may be used translationally to test specific theories; and to help pharma investigators to understand how biomarkers can be used to accelerate treatment development.
Physical Description:1 Online-Ressource (XXIII, 831 p. 146 illus., 127 illus. in color.)
ISBN:9783031694912
ISSN:2190-5223 ;